medical grade actives
Gold-standard ingredients for UTI prevention.
This is what evidence-based prevention looks like.
UTI Biome Shield™
cranberry PACs
cranberry PACs
The Double-Action Shield: 100% bioavailable PACs block bacteria at TWO attachment points. Active in 4–6 hours, lasts up to 12.
d-mannose
d-mannose
The Natural Defender: Binds directly to E. coli within 30 minutes, flushing them out during urination.
vitamin D3
vitamin D3
The Barrier Fortifier: Plant-based D3 strengthens your bladder wall and supports tissue repair.
zinc
zinc
The Immune Activator: Empowers your immune cells to actively clear bacterial infections.
polyphenols
polyphenols
The Biofilm Disruptor: Breaks down bacterial biofilms while promoting beneficial flora.
UTI Biome Shield™ Prevention Actives
- Protection against UTI-causing bacteria, active within 4-6 hours, lasting 12 hours
- Bind and block TWO distinct receptors on bacterial fimbriae (arms), so that bacteria can't attach and are flushed out of the body.
- They directly alter makeup of the gut and urogenital biome by feeding beneficial bacteria, crowding out UTI-causing bugs and down regulating the virulence factors that help them cause infections.
**Per the FDA, consuming 500 mg each day of cranberry dietary supplement may help reduce the risk of recurrent urinary tract infection (UTI) in healthy women.
- Provides early protection against UTI-causing bacteria, active 30 minutes post-ingestion, lasting 6 hours
- binds to Type 1 E. coli receptor arms, allowing them to be flushed out of the body.
- Prebiotic support healthy gut bacteria.
- Urothelial repair
- Boosting immune regulation
38mg per BL-DMAC verification A-type soluble PACs from 100% cranberry juice.
The highest concentration of bioavailable proanthocyanidins (PACs) you can get. Patented double extraction of the active compounds in cranberry juice and whole fruit means PACs are 100% bioavailable.
PACs play an integral role in bacterial anti-adhesion and UTI prevention, binding to TWO distinct receptors on bacterial fimbriae (arms), so that bacteria can't attach and are flushed out of the body.
Naturally occurring sugar present in many fruits and vegetables and is an important part of human metabolism, bacterial anti-adhesion and urinary tract health.
D-Mannose binds to Type 1 E. coli receptor arms, allowing them to be flushed out of the body. There is new evidence that it acts as a prebiotic in the gut to support healthy bacteria.
Lichens are a rare, plant based source of vitamin D3, the biologically active form of cholecalciferol. Vitamin D3 fortifies the bladder wall barrier by promoting cellular tight junctions, urothelial repair, immune regulation and preventing UTIs. It has a regulatory role in acute and recurrent infections especially in women of reproductive age.
Zinc deficiency has been linked to recurrent UTIs. Cells in our immune system known as macrophages deploy zinc to clear bacterial infections. Taking micronutrient supplements such as zinc, may assist in preventing UTIs.
UTI Biome Shield contains the full complement of anti-oxidant and anti-inflammatory polyphenols found in whole fruit rendered in a patented double extraction technique.
These important molecules help reduce oxidative stress and inflammation, aid in the disruption and prevention of biofilms and strengthen the bladder wall.
- Complete whole fruit polyphenol profile (flavonols, flavon-3-ols, phenolic acids, anthocyanidins)
The Science of UTI Prevention
Clinically proven ingredients. One daily ritual. Spot treatment before intimacy.
What is PACphenol?
A patented double extraction yields the highest concentration of bioavailable proanthocyanidins (PACs) you can get. PACs play an integral role in bacterial anti-adhesion and UTI prevention.
What is BioBlocD3?
While basic d-mannose supplements offer partial benefits, Good Kitty's UTI Biome Shield advanced formulation with BioblocD3 technology represents the next generation of urinary tract protection.
UTI Biome Shield™ FAQs
Not all PACs (proanthocyanidins) are soluble or bioavailable.
UTI Biome Shield® contains 38 mg of soluble, bioavailable PACs from a cranberry extract enriched using chromatography. This process preserves the full profile of prebiotic antioxidant polyphenols found in whole fruit while removing unwanted compounds like excess sugars, acids, and oxalates.
This highly active cranberry extract works synergistically with d-mannose to block bacterial adhesion, while zinc and vitamin D support the urogenital lining and microbiome for long-term urinary health.
No. You need a standardized 36mg PAC dose. Look at the labels. This is hidden of they don't. Pacran claims PACs but only has 2-5mg of bioavailable PACs.
UTI Biome Shield® is a daily prevention supplement and should not be used to treat an active infection or illness.
If you are experiencing UTI symptoms, contact your doctor for antibiotics. You can continue taking UTI Biome Shield® alongside treatment and after recovery for ongoing prevention.
Daily Defense: Take 1 UTI Biome Shield® capsule daily to support urinary health and microbiome balance.
Before Sex: Take 2 UTI Biome Shield® capsules with water up to 1 hour before sex. Drink a full glass of water after sex. Return to your regular daily dose the following day.
Yes—just space them a few hours apart.
We always recommend checking with your doctor if you have questions about specific medications. The ingredients in UTI Biome Shield® are generally well tolerated and safe for daily use, but your healthcare provider can advise you based on your personal medical history.
No. UUTI Biome Shield® is formulated by urologists but classified as a dietary supplement and is available over-the-counter in the United States.
UTI Biome Shield® is made with ingredients that are widely regarded as safe and well tolerated.
Some people report mild bloating or loose stool when taking high doses of d-mannose. UTI Biome Shield® contains 1000 mg of d-mannose per 2-capsule serving. If you have a sensitive stomach, we recommend taking it with food.
If you are pregnant or nursing, consult your physician before use.
UTI Biome Shield® has a pH of approximately 4.44.
For comparison:
- Water has a pH of 7
- Cranberry juice has a pH of about 2.7
If you are sensitive to acidic foods or beverages, consider taking UTI Biome Shield® with food or alongside an over-the-counter acid neutralizer.
Yes, especially when derived from high-quality sources.
Yes, it is generally recognized as safe and well-tolerated.
D-Mannose is not metabolized like regular sugar, so it does not raise blood glucose levels and is considered safe for people managing diabetes.
If you have a red fruit allergy, consult your doctor before use.
Cranberries naturally contain salicylic acid, the active metabolite of aspirin. While our extraction process removes most sugars, acids, vitamins, and minerals, those with aspirin allergies should use caution and consult a healthcare provider before taking UTI Biome Shield® .
If you take Coumadin (Warfarin) or other non-vitamin K blood thinners, consult your healthcare provider before using UTI Biome Shield. While virtually all vitamin K is removed from our cranberry extract during processing, even small amounts may affect blood thinner effectiveness, so professional guidance is recommended.
During our proprietary extraction process, we remove approximately 90% of oxalates — the compounds in cranberries associated with kidney stones.
UTI Biome Shield® contains only 0.15 mg of oxalates per capsule. A high oxalate food is considered to contain more than 10 mg per serving. Foods under 2 mg per serving are considered low oxalate.
For context, many nuts, grains, fruits, and vegetables contain higher oxalate levels than UTI Biome Shield® .
UTI Biome Shield® supports urinary health and may help reduce UTIs that occur as a result of IC, but it is not a treatment for IC itself.
Because the product has a mild acidity similar to coffee or cola, those sensitive to acidic foods may prefer to take it with food or an acid reducer. Always consult your healthcare provider for appropriate IC management.
