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Our Research

Formulated by doctors.

Backed by science.

Every ingredient in UTI Biome Shield® is clinically studied at doses proven to support urinary tract health. No fillers. No guesswork. Just science.

This is evidence-based prevention.

our medical advisors.

Sharon Knight, MD

Urogynocologist, Pelvic Surgeon | Sutter Health

Many women who experience rUTIs are seeking effective strategies to reduce their reliance on antibiotics. In my practice, I often recommend cranberry and d-mannose. For women who experience UTIs with sexual activity, taking these UTI prevention supplements before or after intercourse can be especially beneficial. However, many cranberry products do not clearly indicate the presence of PACs, making it hard to assess their effectiveness. This particular UTI product offers a concentrated dose of the active cranberry component, combined with d-mannose in a single, convenient capsule.

our medical advisors.

Meghan Blake, MD

The Wellness Pioneer | Stanford

Board-certified physician championing integrative approaches to women's health and intimate wellness. "30 million American women with UTIs deserve better than playing defense"

our medical advisors.

Edward Abratowski, MD

Internal Medicine Physician | Sutter Health

UTI Biome Shield® is a significant advancement in urinary tract health. Its single-dose pill ingeniously combines two of the most potent, science-backed compounds—bioavailable PACs and d-mannose for comprehensive protection, addressing the root causes of infection, including the role of a healthy microbiome and tissue integrity. For patients seeking evidence-based, non-antibiotic approaches to UTI prevention, this is the most advanced solution I've encountered in clinical practice.

our medical advisors.

Tashina Doolin, MSPAS, PA

Physician's Assistant | Tia Health

Specializing in women’s health,  I've seen many patients suffer from recurrent UTIs despite trying various treatments. UTI Biome Shield® is a scientifically proven UTI prevention supplement that offers a real solution, using evidence-based ingredients like polyphenols, D-mannose, vitamin D, and zinc to prevent bacterial adhesion and support immune health. It's effective and well rounded defense that reduces reliance on antibiotics, which can contribute to the preservation of the gut microbiome and long-term health. The product’s commitment to sustainability through eco-conscious packaging is commendable. I’m so excited to start offering my patients a product that actually works! 

Black and white professional portrait of Dr Sharon Knight with glasses and long hair wearing a black top with a subtle neckline detail, smiling at the camera against a dark background.

UTI Biome Shield®

before & after results *testing done by June Bio Laboratories
Comparison of Lactobacillus crispatus percentage before and after using UTI Biome Shield.

UTI Biome Shield®

UTI Biome Shield™

Lactobacillus crispatus (the microbe most associated with a resilient vaginal microbiome) increased to 60.3%, shifting the microbiome toward a healthier, more stable state.

Comparison of bacteria load and microbes before and after using UTI Biome Shield.

Bacteria Microbes

Bacteria Type Balances

Elevated anaerobic + aerobic bacteria associated with recurrent UTIs reduced + microbiome balance shifted toward predominantly beneficial Lactobacillus species.

Comparison of bacteria load before and after using UTI Biome Shield

Bacteria Load Panel

Bacteria Load Panel

Microbial profile shows non-beneficial bacteria highly decreased and E. coli reduced to 0.0% — a clinically meaningful microbial shift.

Amy Howell, PhD, Philip E. Marucci Center for Blueberry & Cranberry Research, Rutgers University

"Many lower cost supplements contain the pomace fiber material left over after the juice is removed and are not as effective at preventing bacterial adhesion as compared to a pure juice-based product.”

Edward Abratowski, MD Internal Medicine Physician at Sutter Health

"UTI Biome Shield® represents a significant advancement in urinary tract health. For patients seeking evidence-based, non-antibiotic approaches to UTI prevention, this is the most advanced solution I've encountered in clinical practice."

Michael Gregor, MD, FACLM

"Your gut remains stubbornly colonized with these bad bladder bugs and only bioavailable cranberry products appear to reduce the recurrence of bladder infections by about 35%. Not as effective as antibiotics, but cranberries don’t foster antibiotic resistance, and have fewer side effects."

UTI Biome Shield® vs. E.coli

Urine culture results with and without UTI Biome Shield® 48 hours after sex.

shop UTI prevention
Bacterial culture plate with red agar and gold colonies on a brown background. A laboratory petri dish labeled “E. coli testing” showing visible bacterial growth, indicating a positive bacterial result.

Without UTI Prevention: Significant E. coli growth 48 hours after sex.

A laboratory petri dish labeled “E. coli testing” showing no bacterial growth — the surface is clean and clear, indicating a successful antibacterial result

With UTI Biome Shield®: E. coli not present 48 hours after sex.

Use the left and right arrow keys to navigate between before and after photos.

Open-label pilot; urine collected 48h post-coital; cultured on MacConkey agar; endpoint log10 CFU/mL. Dietary supplement supports urinary tract health and is not intended to diagnose, treat, cure, or prevent disease.

clinical trials