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medical compounds and why our gut & vaginal microbiome needs them

PRESCRIPTION STRENGTH BIOACTIVES

proanthocyanidins

PACs - Not all cranberry ingredients are created equal. The science only holds up when PACs are delivered in the right type and dose (36mg per BL-DMAC verification proanthocyanidins (A-type soluble PACs) to block bacteria. PACs play an integral role in bacterial anti-adhesion and UTI prevention, binding to TWO distinct receptors on bacterial fimbriae (arms), so that bacteria can't attach and are flushed out of the body.

d-mannose

Naturally occurring sugar found in fruits and vegetables and plays a key role in urinary tract health. It works by binding to the Type 1 receptor arms on E. coli, preventing them from attaching to your bladder walls so they can be flushed out. Emerging research also shows D-mannose supports gut health by acting as a gentle prebiotic.

Vitamin D3

Lichens are a rare, plant based source of vitamin D3, the biologically active form of cholecalciferol. Vitamin D3 fortifies the bladder wall barrier by promoting cellular tight junctions, urothelial repair, immune regulation and preventing UTIs. It has a regulatory role in acute and recurrent infections especially in women of reproductive age.

zinc picolinate

Zinc deficiency has been linked to recurrent UTIs. Cells in our immune system known as macrophages deploy zinc to clear bacterial infections. Taking micronutrient supplements such as zinc, may assist in preventing UTIs.

polyphenols

These important molecules help reduce oxidative stress and inflammation, aid in the disruption and prevention of biofilms and strengthen the bladder wall. They directly alter makeup of the gut and urogenital biome by feeding beneficial bacteria, crowding out UTI-causing bugs and down regulating the virulence factors that help them cause infections.

BioBlocD3™ & PACphenol™

UTI Biome Shield

  • 250 mg BL-DMAC verified Proanthocyanidins (A-type soluble PACs)
  • Extracted from North American Cranberry concentrated juice (Vaccinium Macrocarpon)
  • Complete whole fruit polyphenol profile (flavonols, flavon-3-ols, phenolic acids, anthocyanidins)

Provides early protection against UTI-causing bacteria, active 30 minutes post-ingestion, lasting 12 hours

Natural cranberries growing on green shrubs with small oval red berries nestled among the leaves, showcasing the natural source of proanthocyanidins used in UTI prevention formulas.

ADVANCED UTI PROTECTION

What is PACphenol?

A patented double extraction yields the highest concentration of bioavailable proanthocyanidins (PACs) you can get. PACs play an integral role in bacterial anti-adhesion and UTI prevention.

Close-up of sliced cranberries showing their characteristic internal star pattern in various shades of deep red and pink against a dark background, highlighting a key natural ingredient in UTI prevention supplements.
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cranberry PACs vs cranberry for UTI prevention

36mg of PACs are the only scientifically proven compound to prevent Urinary Tract Infections.

Proanthocyanidins (PACs) are the active compounds in cranberries that prevent bacteria from sticking to the bladder wall. But most cranberry juice contains too little to be effective.

PAC Faqs

Not all cranberry ingredients are created equal. The science only holds up when PACs are delivered in the right type (A-type PACs) and in the right dose to stop bacteria from latching onto your bladder walls.

At Good Kitty Co, we use clinically validated PAC levels to ensure prevention, not placebo.

cranberry proanthocyanidins - PACs

Can I just drink cranberry juice for UTIs?

No. You need a standardized 36mg PAC dose. Look at the labels. This is hidden of they don't. Pacran claims PACs but only has 2-5mg of bioavailable PACs.

Are PACs safe for daily use?

Yes, especially when derived from high-quality sources.

How to Spot the Right Supplement?

Look for supplements with 36mg of soluble, standardized PACs. These are clinically shown to reduce UTI risk.

What supplement works best for post-sex UTIs?

UTI Biome Shield Clinically proven UTI prevention with 38mg of bioavailable PACs in one pill.

Multi-action defense system powered by our exclusive PACphenol™ and BioBlocD3™, engineered to stop UTIs before they start. Unlike antibiotics that disrupt your microbiome, our physician-developed formula supports beneficial bacteria, neutralizes E. coli introduced during intimate moments, and addresses the gut reservoir of UTI-causing bacteria, one of the main root causes of recurrence.

DETAILS: Our clinically proven formula combines PACphenol™ (38mg soluble PACs and polyphenols) with BioBlocD3™ (d-mannose complexed with vitamin D3 and zinc) for complete UTI defense. Our formula doesn't just fight bacteria—prebiotics restore your microbiome's natural balance, bioactives heal damaged bladder tissue and strengthen your immune response.

  • BLOCK E. coli receptor sites
  • ELIMINATE biofilm
  • REPAIR bladder tissue
  • OPTIMZE microbiome
Close-up of d-mannose
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What Is D-Mannose?

D-Mannose is a Natural Ally Against UTIs

D-Mannose is a naturally occurring sugar that attaches to E. coli bacteria, preventing them from sticking to the bladder wall and flushing them out through urination.

Why It Works : Unlike glucose, D-Mannose is not metabolized the same way and does not spike blood sugar. Clinical studies show that it helps reduce recurrent UTIs in women.

How to Use D-Mannose for UTI Prevention

  • Take daily with water
  • Best absorbed on an empty stomach
  • Safe for long-term use

D-Mannose Faqs

Is D-Mannose safe?

Yes, it is generally recognized as safe and well-tolerated.

Can I use D-Mannose with antibiotics?

Yes, but it's most effective as a prevention tool, not a treatment.

I have diabetes.

D-Mannose is not metabolized like regular sugar, so it does not raise blood glucose levels and is considered safe for people managing diabetes.*

Banner image showing white supplement tablets with text overlay 'ADVANCED UTI PROTECTION' and 'What is BioBlockD3?' explaining how UTI Biome Shield with BioblocD3 technology represents the next generation of urinary tract protection. A 'learn more' button appears below the description.

ADVANCED UTI PROTECTION

What is BioBlocD3?

While basic d-mannose supplements offer partial benefits, Good Kitty's UTI Biome Shield advanced formulation with BioblocD3 technology represents the next generation of urinary tract protection. 

Burgundy UTI biome Shield capsules being poured from a purple pouch into a hammered gold vessel with the Good Kitty logo. Several capsules rest on a marble surface beside the gold container.
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Gold-Standard Ingredients for UTI Prevention

What Makes a Supplement Effective for UTI Prevention

Look for formulas with:

  • 36mg of soluble PACs
  • High bioavailability
  • Zero fillers or sugar

Daily Use vs. Spot Treatment

The best results come from daily use. Prevention works over time—don’t wait for symptoms to start.

  • Can I take these with antibiotics? Yes—just space them a few hours apart.
  • Are there side effects? Generally no, but always consult your doctor.

 

one pill prevents UTIs

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clinical trials

WHAT THE EXPERTS SAY

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Benefits

Anti-Adhesion Activity (AAA), Bioavailability
Prevention
Microbiome Optimization
Downregulation of E. Coli Virulence Factors
Innate Immune Function
Urothelial Repair

Bioactives

PACs
d-Mannose
Polyphenols
Vitamin D
Zinc