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Bacterial culture plate with red agar and gold colonies on a brown background. A laboratory petri dish labeled “E. coli testing” showing visible bacterial growth, indicating a positive bacterial result.

block antibiotic resistant E.coli

ALARMING FACTS

  • 70% of UTI-causing bacteria evade multiple antibiotics
  • 30% multi-drug resistant
  • UTIs are the #2 cause of antibiotic prescriptions
  • 60% of recurrent UTI patients are put on long-term prophylactic antibiotics

Our revolutionary UTI BIOME SHIELD is medical-grade formula is active in 30 minutes and creates a 12-hour bacterial shield—without triggering resistance.

break the uti cycle for Good

PRESCRIPTION STRENGTH BIOACTIVES

minutes - rapid shield

BioBlocD3 - Our time release formula starts working within 30 minutes providing immediate UTI protection, coating and neutralizing bacteria.

hours - dual defense

Dual Defense PACphenol both weakens type-1 bacterial fimbriae and binds p-type receptors on harmful bacteria. Unable to attach to the bladder wall, they are flushed from the body when you urinate.

days - repair & renew

UTI-causing bacteria are downregulated in the gut, reducing future infection risk. Bladder wall damage is repaired as biofilm breaks down.

weeks - immune strength

Vitamin D strengthens the bladder wall while zinc picolinate and polyphenols enhance immunity, reduce inflammation, and fight free radicals.

months - microbiome balance

Beneficial bacteria thrive in the gut and urogenital microbiome with prebiotic support.

beyond - total vaginal health

A balanced microbiome supports long-term protection against UTIs, candida, and other infections.

multi targeted approach: prevent, repair & protect

UTI prevention

UTI Biome Shield

Bioavailable PACphenol™ & BioBlocD3™ simultaneously targets bacterial fimbriae and epithelial receptor sites, creating a multi-action barrier that disrupts adhesion mechanisms that facilitate bacterial attachment and infection.

urothelial repair

Bacteria Type Balances

PACs, polyphenols and micronutrients vitamin D3 and zinc help rebuild your defenses, healing damaged bladder tissue, strengthening your immune response, and breaking down biofilm.

Woman in a brown bikini sitting on a couch with wooden paneling.

microbiome optimization

Bacteria Load Panel

Prebiotics & polyphenols enhance immunity and restore microbial diversity, supporting beneficial bacteria in the gut, vagina, and urinary tract, balancing your gut and vaginal microbiome.

good kitty vs. e.coli

Urine culture results 48 hours after sex. Open-label pilot; urine collected 48h post-coital; cultured on MacConkey agar; endpoint log10 CFU/mL. Results vary. Dietary supplement supports urinary tract health; not intended to diagnose, treat, cure, or prevent disease.

do you have a UTI?
Bacterial culture plate with red agar and gold colonies on a brown background. A laboratory petri dish labeled “E. coli testing” showing visible bacterial growth, indicating a positive bacterial result.

No Supplement: urine culture plate showing heavy E. coli growth 48 hours after intercourse

A laboratory petri dish labeled “E. coli testing” showing no bacterial growth — the surface is clean and clear, indicating a successful antibacterial result

UTI Biome Shield: urine culture plate showing minimal E. coli colonies 48 hours after intercourse, UTI Biome Shield group.

Use the left and right arrow keys to navigate between before and after photos.

UTI Biome Shield

before & after results *testing done by June Bio Laboratories
Comparison of Lactobacillus crispatus percentage before and after using UTI Biome Shield.

UTI Biome Shield

UTI Biome Shield

Lactobacillus crispatus (the microbe most associated with a resilient vaginal microbiome) increased to 60.3%, shifting the microbiome toward a healthier, more stable state.

Comparison of bacteria load and microbes before and after using UTI Biome Shield.

Bacteria Microbes

Bacteria Type Balances

Elevated anaerobic + aerobic bacteria associated with recurrent UTIs reduced + microbiome balance shifted toward predominantly beneficial Lactobacillus species.

Comparison of bacteria load before and after using UTI Biome Shield

Bacteria Load Panel

Bacteria Load Panel

Microbial profile shows non-beneficial bacteria highly decreased and E. coli reduced to 0.0% — a clinically meaningful microbial shift.

Banner image showing white supplement tablets with text overlay 'ADVANCED UTI PROTECTION' and 'What is BioBlockD3?' explaining how UTI Biome Shield with BioblocD3 technology represents the next generation of urinary tract protection. A 'learn more' button appears below the description.

ADVANCED UTI PROTECTION

What is BioBlocD3?

While basic d-mannose supplements offer partial benefits, Good Kitty's UTI Biome Shield advanced formulation with BioblocD3 technology represents the next generation of urinary tract protection. 

Natural cranberries growing on green shrubs with small oval red berries nestled among the leaves, showcasing the natural source of proanthocyanidins used in UTI prevention formulas.

TOTAL VAGINAL HEALTH

What is PACphenol?

A patented double extraction yields the highest concentration of bioavailable proanthocyanidins (PACs) you can get. PACs play an integral role in bacterial anti-adhesion and UTI prevention.

ingredients glossary

PACphenol™

  • Protection against UTI-causing bacteria, active within 4-6 hours, lasting 12 hours
  • Bind and block TWO distinct receptors on bacterial fimbriae (arms), so that bacteria can't attach and are flushed out of the body.
  • They directly alter makeup of the gut and urogenital biome by feeding beneficial bacteria, crowding out UTI-causing bugs and down regulating the virulence factors that help them cause infections.


**Per the FDA, consuming 500 mg each day of cranberry dietary supplement may help reduce the risk of recurrent urinary tract infection (UTI) in healthy women.


BioBlocD3™

  • Provides early protection against UTI-causing bacteria, active 30 minutes post-ingestion, lasting 6 hours
  • binds to Type 1 E. coli receptor arms, allowing them to be flushed out of the body.
  • Prebiotic support healthy gut bacteria.
  • Urothelial repair
  • Boosting immune regulation


Proanthocyanidins (PACs)

38mg per BL-DMAC verification A-type soluble PACs from 100% cranberry juice.


The highest concentration of bioavailable proanthocyanidins (PACs) you can get. Patented double extraction of the active compounds in cranberry juice and whole fruit means PACs are 100% bioavailable.

PACs play an integral role in bacterial anti-adhesion and UTI prevention, binding to TWO distinct receptors on bacterial fimbriae (arms), so that bacteria can't attach and are flushed out of the body.



D-mannose

Naturally occurring sugar present in many fruits and vegetables and is an important part of human metabolism, bacterial anti-adhesion and urinary tract health.


D-Mannose binds to Type 1 E. coli receptor arms, allowing them to be flushed out of the body. There is new evidence that it acts as a prebiotic in the gut to support healthy bacteria.


Vitamin D3

Lichens are a rare, plant based source of vitamin D3, the biologically active form of cholecalciferol. Vitamin D3 fortifies the bladder wall barrier by promoting cellular tight junctions, urothelial repair, immune regulation and preventing UTIs. It has a regulatory role in acute and recurrent infections especially in women of reproductive age.

Zinc Picolinate

Zinc deficiency has been linked to recurrent UTIs. Cells in our immune system known as macrophages deploy zinc to clear bacterial infections. Taking micronutrient supplements such as zinc, may assist in preventing UTIs.

Polyphenols

UTI Biome Shield contains the full complement of anti-oxidant and anti-inflammatory polyphenols found in whole fruit rendered in a patented double extraction technique.


These important molecules help reduce oxidative stress and inflammation, aid in the disruption and prevention of biofilms and strengthen the bladder wall.


  • Complete whole fruit polyphenol profile (flavonols, flavon-3-ols, phenolic acids, anthocyanidins)

Amy Howell, PhD, Philip E. Marucci Center for Blueberry & Cranberry Research, Rutgers University

"Many lower cost supplements contain the pomace fiber material left over after the juice is removed and are not as effective at preventing bacterial adhesion as compared to a pure juice-based product.”

Edward Abratowski, MD Internal Medicine Physician at Sutter Health

"UTI Biome Shield represents a significant advancement in urinary tract health. For patients seeking evidence-based, non-antibiotic approaches to UTI prevention, this is the most advanced solution I've encountered in clinical practice."

Michael Gregor, MD, FACLM

"Your gut remains stubbornly colonized with these bad bladder bugs and only bioavailable cranberry products appear to reduce the recurrence of bladder infections by about 35%. Not as effective as antibiotics, but cranberries don’t foster antibiotic resistance, and have fewer side effects."

Manicured hands with glittery nail polish holding colorful antibiotic pills with text overlay stating '70% OF BACTERIA IS DRUG RESISTANT' and 'are preventive antibiotics worth it?' The image explains the changing landscape of UTI prevention due to antibiotic resistance, with a 'learn more' button.

are preventive antibiotics good?

While traditional prevention has often relied on prophylactic antibiotics, the landscape is rapidly changing due to alarming rates of antibiotic resistance.

Medical examination table in a clinical setting with medical equipment on the wall.

utis after sex?

Sexual activity itself doesn't cause UTIs. Rather, it creates conditions that make bacterial transfer more likely, especially if you have underlying risk factors.

clinical trials

WHAT THE EXPERTS SAY

Benefits

Anti-Adhesion Activity (AAA), Bioavailability
Prevention
Microbiome Optimization
Downregulation of E. Coli Virulence Factors
Innate Immune Function
Urothelial Repair

Bioactives

PACs
d-Mannose
Polyphenols
Vitamin D
Zinc